The dragon is based on the N-terminal heparin-binding domain of amyloid precursor protein (APP). APP plays a crucial role in the Alzheimer's disease pathogenesis.
Freitag, 29. Juli 2011
1MWP: Dragon with a Flower
The dragon is based on the N-terminal heparin-binding domain of amyloid precursor protein (APP). APP plays a crucial role in the Alzheimer's disease pathogenesis.
Donnerstag, 28. Juli 2011
2OCJ: Pair Skating
3L1E: Eskimo
AlphaA crystallin is a structure protein which can be found in the eye lens. Alpha crystallin can also act as a chaperon (meaning that it can assist proteins to acquire a certain 3D structure) and prevent the precipitation of denatured proteins. This property is suggested to contribute to the maintenance of lens transparency and to the prevention from cataracts.[1]
There seems to be a good reason why an Eskimo is shown in this drawing. Interestingly, cataracts and glaucoma are prevalent in Alaska Native people.[2]
From Protein to Art
Here is an example of how I produce art out of protein molecules.
In this image you see the 2-nd PDZ-domain of the Mint1 protein "Cartoons"-representation, (2) in a "Cartoons"-representation with a reduced ribbon width, and (3) the designed variant of the protein.
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